Product & ReviewsAntibodies

CD2 (HIT11) Antibody

Product Details

Cat. No.
250989
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Abbiotec

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Description

The CD2 (HIT11) antibody recognizes a 50-kDa type-I single-chain transmembrane glycoprotein called LFA-2 (lymphocyte function associated antigen-2) or sheep red blood cell (SRBC) receptor. The CD2 antigen is expressed on 70-80% of peripheral blood lymphocytes and 80%-90% of thymocytes and NK cells. The primary ligand for CD2 is CD58 (LFA-3) despite binding to CD48, CD59 and CD15. The CD2 antigen plays a role in T cell signaling and in lymphocyte adhesion, and is an alternative pathway of T cell activation. There are two forms of CD2, a membrane form on cell surface and a soluble form in serum.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Clone: HIT11
  • Conjugate: FITC-conjugated Antibody
  • Isotype: mouse IgG1
  • Gene: P06729

Handling

  • Quantity: 2 ml
  • Storage: Store at 4°C. Product is guaranteed 6 months from the date of shipment.

Applications

  • Flow Cytometry (FC)
Specificity rating
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