Product & ReviewsAntibodies
CD2 (HIT11) Antibody
Product Details
- Cat. No.
- 251045
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The CD2 (HIT11) antibody recognizes a 50-kDa type-I single-chain transmembrane glycoprotein called LFA-2 (lymphocyte function associated antigen-2) or sheep red blood cell (SRBC) receptor. The CD2 antigen is expressed on 70-80% of peripheral blood lymphocytes and 80%-90% of thymocytes and NK cells. The primary ligand for CD2 is CD58 (LFA-3) despite binding to CD48, CD59 and CD15. The CD2 antigen plays a role in T cell signaling and in lymphocyte adhesion, and is an alternative pathway of T cell activation. There are two forms of CD2, a membrane form on cell surface and a soluble form in serum.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Clone: HIT11
- Conjugate: PE-conjugated Antibody
- Isotype: mouse IgG1
- Gene: P06729
Handling
- Quantity: 2 ml
- Storage: Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Applications
- Flow Cytometry (FC)