Product & ReviewsAntibodies

CD20 antibody

Product Details

Cat. No.
orb10307
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Biorbyt

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Description

CD20 antigen is a type of tumor marker. Also called CD20. There's a protein found on B cells (a type of white blood cell). It may be found in higher than normal amounts in patients with certain types of B-cell lymphomas and leukemias. Measuring the amount of CD20 antigen on blood cells may help to diagnose cancer or plan cancer treatment.The protein has no known natural ligand[8] and its function is to enable optimal B-cell immune response; specifically against T-independent antigens.It is suspected that it acts as a calcium channel in the cell membrane.It has been shown that CD20 also plays a role in the microenvironmental interactions of B cells.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human, Mouse, Rat
  • Clone: NULL
  • Conjugate: Unconjugated
  • Isotype: IgG
  • Gene: 931

Handling

  • Quantity: 100 ?g
  • Storage: Store at 4°C for up to two weeks. For long term storage; aliquot and store at -20°C; avoid freeze/thaw cycles.
  • Buffer: 10 mM PBS; 0.02% sodium azide

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
  • Western Blotting (WB)
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