Product & ReviewsAntibodies

CD203c-PE, 97A6, 2 mL, ASR

Product Details

Cat. No.
IM3575
Type
Flow Cytometry Reagents
Clonality
Monoclonal
Host
Mouse
Beckman Coulter Life Sciences

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Description

The CD203c molecule is a type II transmembrane protein that belongs to the ectonucleotide pyrophosphatase / phosphosdiesterase 3 (E-NPP3) family of enzymes involved in hydrolysis of oligonucleotides, nucleoside phosphates, and NAD. Basophils and mast cells are hematopoietic effector cells involved in allergic and inflammatory reactions. Both cell types highly express the high affinity IgE receptor. The CD203c is expressed on human peripheral blood basophils, but not on other blood cells. It is also expressed by mature mast cells, and by CD34+ bone marrow progenitors of basophils and mast cells. Moreover, the CD203c antigen is up-regulated after activation of basophils by anti-IgE antibodies and allergens.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: CD203c
  • Clone: 97A6
  • Conjugate: PE
  • Isotype: IgG1

Handling

  • Quantity: 2 mL

Applications

  • Flow Cytometry (FC)
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Sensitivity rating
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