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The CD23 antigen (also called B6) is a 45 kDa transmembrane glycoprotein associated with MHC Class II antigen, which belongs to the C-type lectin family. CD23 is the low affinity receptor for IgE (FcεRII). CD23 antigen is expressed on B lymphocytes, monocytes and follicular dendritic cells (FDC). Expression of CD23 by B lymphocytes is up-regulated following mitogen or antigen activation. Soluble forms of CD23 are generated by proteolytic cleavage of the membrane molecule.*Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.