CD25 Antibody
Product Details
- Cat. No.
- 251220
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Interleukin-2 receptor subunit alpha (CD25) is a receptor for interleukin-2. CD25 is a non-covalent dimer consisting of an alpha and a beta subunit. CD25 exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Genetic variations in CD25 are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10), a multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD25.
- Isotype: Rabbit Ig
- Gene: P01589; NP_000408
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)