CD25-SuperNova v428, 0.5ml ASR
Product Details
- Cat. No.
- C69245
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The CD25 antigen (IL-2Rα chain, Tac or p55) is a single-chain glycoprotein with a molecular weight of 55 kDa which is the low affinity receptor for IL-2 (IL-2Rα or IL-2R1). In conjunction with CD122 (IL-2Rβ, p75) and CD132 (IL-2Rγ, p64), CD25 antigen forms the high-affinity IL-2R complex. CD25 is highly expressed on regulatory CD4-positive T lymphocytes and undetected on resting CD8 positive lymphocytes. However, all activated T lymphocytes express the CD25 protein. CD25 is also found on a subset of B cells (CD20 positive), on activated monocytes and macrophages, and on T cell clones. It is also expressed on NK cells enriched from peripheral blood lymphocytes by culturing in the presence of IL-2. It is absent from thymocytes, granulocytes, monocytes, resting NK cells, platelets and erythrocytes.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mink, Sheep (Ovine), Squirrel Monkey
- Antigen: CD25
- Clone: B1.49.9
- Conjugate: SNv428
- Isotype: IgG2a
Handling
- Quantity: 0.5 mL
Applications
- Flow Cytometry (FC)