Product & ReviewsAntibodies
CD261 Antibody
Product Details
- Cat. No.
- 251233
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
CD261 DR4/TRAIL-R1 (CD261) is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to activated CD261. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD261.
- Isotype: Rabbit Ig
- Gene: O00220
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)