Product & ReviewsAntibodies
CD265 Antibody
Product Details
- Cat. No.
- 251954
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Tumor necrosis factor receptor superfamily member 11A (CD265) is a receptor for TNFSF11/RANKL/TRANCE/OPGL. CD265 is essential for RANKL-mediated osteoclastogenesis. CD265 is involved in the regulation of interactions between T-cells and dendritic cells. Defects in CD265 are the cause of familial expansile osteolysis (FEO). FEO is a rare autosomal dominant bone disorder characterized by focal areas of increased bone remodeling. The osteolytic lesions develop usually in the long bones during early adulthood.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD265.
- Isotype: Rabbit Ig
- Gene: Q9Y6Q6
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)