Product & ReviewsAntibodies
CD274 antibody
Product Details
- Cat. No.
- orb10162
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
WB analysis of mouse heart (lane 1), rat muscle (lane 2), rat lung (lane 3), rat thymus (lane 4), rat lymph node (lane 5) using CD274 antibody (2.5 ug/ml)
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Description
The CD274 antibody is commonly known as PD-L1. B7-H1 is the target ; it is a member of the B7 family; and belongs to the Ig superfamily. B7-H1 is expressed on a majority of leukocytes. CD274 is also Involved in the signaling ; it also helps in the production of IL10 and IFNG; in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Clone: NULL
- Conjugate: Unconjugated
- Isotype: IgG
- Gene: 29126
Handling
- Quantity: 100 ?g
- Storage: Store at 4°C for up to two weeks. For long term storage; aliquot and store at -20°C; avoid freeze/thaw cycles.
- Buffer: 10 mM PBS; 0.02% sodium azide
Applications
- ELISA (ELISA)
- Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
- Western Blotting (WB)
