CD276 Antibody, anti-human, APC

Clone FM276 reacts with human CD276 (B7-H3), a type I transmembrane protein expressed at low levels in human liver, lung, bladder, testis, prostate, breast, placenta, lymphoid organs, and many human cancers. Surface expression can be induced on T cells, natural killer cells, and macrophages as well as on dendritic cells (DC) by IFN-γ and on monocytes by granulocyte macrophage colony-stimulating factor (GM-CSF) and interleukin 4 (IL-4). B7-H3 has been shown to function as costimulatory molecule for T cell activation by inducing T cell proliferation and IFN-γ production.

• Clonality: Monoclonal
• Host: Mouse
• Reactivity: Human
• Antigen: CD276
• Clone: FM276
• Conjugate: APC
• Isotype: mouse IgG2bκ

• Storage: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
• Specificity: 5

• Flow Cytometry (FC)