Product & ReviewsAntibodies

CD38-PB, LS198-4-3, 50 Tests, CE

Product Details

Cat. No.
B92396
Type
Flow Cytometry Reagents
Clonality
Monoclonal
Host
Mouse
Beckman Coulter Life Sciences

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Description

The CD38 antigen is a 45 kDa single chain type II integral membrane glycoprotein, with the NH2-terminus inside the cytoplasm. CD38 is an enzyme with several activities such as NAD glycohydrolase, ADP ribosylcyclase and cyclic ADP ribose hydrolase. CD38 is expressed on activated T and B lymphocytes, NK cells, monocytes, plasma cells and medullary thymocytes. CD38 expression appears to depend on the differentiation and activation of the cell. In the B cell lineage, CD38 is expressed in early stages of B-cell ontogeny, lost during maturation and re-expressed upon terminal differentiation to plasma cells. Similarly, CD38 is expressed on thymocytes and at a high level on activated T cells. Most mature resting lymphocytes of both B and T lineages do not express the CD38 antigen. CD38 is widely used as a marker to study T and B lymphocyte activation.*Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: CD38
  • Clone: LS198-4-3
  • Conjugate: Pacific Blue*
  • Isotype: IgG1

Handling

  • Quantity: 50 tests

Applications

  • Flow Cytometry (FC)
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