Product & ReviewsAntibodies

CD4 (8G1B12) Antibody

Product Details

Cat. No.
253281
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Abbiotec

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Description

CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human, Mouse, Rat
  • Antigen: 193-aa recombinant protein within the N-term region of human CD4.
  • Clone: 8G1B12
  • Isotype: Mouse IgG1
  • Gene: P01730

Handling

  • Quantity: 0.1 mg
  • Storage: Store at 4°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Western Blotting (WB)
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