CD4 (8G1B12) Antibody
Product Details
- Cat. No.
- 253281
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse, Rat
- Antigen: 193-aa recombinant protein within the N-term region of human CD4.
- Clone: 8G1B12
- Isotype: Mouse IgG1
- Gene: P01730
Handling
- Quantity: 0.1 mg
- Storage: Store at 4°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)