CD4-PE, 13B8.2, 2 mL, ASR
Product Details
- Cat. No.
- IM0449U
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The CD4 antigen is a single-chain transmembrane glycoprotein with a 59 kDa molecular weight. CD4 binds to a non-polymorphic region of MHC Class II molecules and is a co-receptor in MHC Class II restricted antigen-induced activation. CD4 is expressed on the T "helper" lymphocytes. It is present on most thymocytes where it is frequently co-expressed with CD8. CD4 is also expressed on all monocytes, although with a lower density than on T lymphocytes. CD4+ T lymphocytes are active in inducing and helping the synthesis of immunoglobulins by B cells. CD4 is a receptor for the Human Immunodeficiency Virus type I (HIV-1) envelope protein gp120.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Baboon, Baboon, Human
- Antigen: CD4
- Clone: 13B8.2
- Conjugate: PE
- Isotype: IgG1
Handling
- Quantity: 2 mL
Applications
- Flow Cytometry (FC)