Product & ReviewsAntibodies

CD4-PE, 13B8.2, 2 mL, ASR

Product Details

Cat. No.
IM0449U
Type
Flow Cytometry Reagents
Clonality
Monoclonal
Host
Mouse
Beckman Coulter Life Sciences

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Description

The CD4 antigen is a single-chain transmembrane glycoprotein with a 59 kDa molecular weight. CD4 binds to a non-polymorphic region of MHC Class II molecules and is a co-receptor in MHC Class II restricted antigen-induced activation. CD4 is expressed on the T "helper" lymphocytes. It is present on most thymocytes where it is frequently co-expressed with CD8. CD4 is also expressed on all monocytes, although with a lower density than on T lymphocytes. CD4+ T lymphocytes are active in inducing and helping the synthesis of immunoglobulins by B cells. CD4 is a receptor for the Human Immunodeficiency Virus type I (HIV-1) envelope protein gp120.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Baboon, Baboon, Human
  • Antigen: CD4
  • Clone: 13B8.2
  • Conjugate: PE
  • Isotype: IgG1

Handling

  • Quantity: 2 mL

Applications

  • Flow Cytometry (FC)
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