Product & ReviewsAntibodies
CD40 (9G10) Antibody
Product Details
- Cat. No.
- 252904
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CD40 is a 48-kDa type-I single chain transmembrane glycoprotein expressed on normal and neoplastic B cells, but not on terminally differentiated plasma cells. CD40 antigen is also present on Hodgkin and Reed-Sternberg cells, follicular dendritic cells, some macrophages, basal epithelial cells and endothelial cells. The ligand for CD40 is CD154 (CD40L). CD40 is involved in growth, differentiation, isotype-switching on B cells and rescuing B cells from apoptosis.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of CD40 expressed in E. coli.
- Clone: 9G10
- Isotype: Mouse IgG1
- Gene: P25942
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunofluorescence (IF)