Product & ReviewsAntibodies
CD40 (HI40a) Antibody
Product Details
- Cat. No.
- 250961
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The CD40 (HI40a) antibody recognizes a 48-kDa type-I single chain transmembrane glycoprotein expressed on normal and neoplastic B cells, but not on terminally differentiated plasma cells. CD40 antigen is also present on Hodgkin and Reed-Sternberg cells, follicular dendritic cells, some macrophages, basal epithelial cells and endothelial cells. The ligand for CD40 is CD154 (CD40L). CD40 is involved in growth, differentiation, isotype-switching on B cells and rescuing B cells from apoptosis.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Clone: HI40a
- Isotype: mouse IgG2b
- Gene: P25942
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Flow Cytometry (FC)