CD41-ECD, P2, 100 Tests, RUO
Product Details
- Cat. No.
- 6607117
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our Antibody Directory.
Description
The CD41 antigen (platelet GPIIb; IIb integrin) is a transmembrane glycoprotein composed of two chains GPIIbα (120 kDa) and GPIIbβ (23 kDa) linked by one disulfide bond. CD41 is always non-covalently associated with CD61 (platelet GPIIIa, β3 integrin), to form the GPIIb-IIIa (CD41/CD61) complex. CD41 is expressed by platelets, megakaryocytes and a small subset of CD34+ cells, suggesting that CD41/CD61 is one of the earliest markers of the megakaryocytic lineage. The resting form of the CD41/CD61 complex binds to immobilized fibrinogen and upon platelet activation, the complex becomes a receptor for soluble fibrinogen, fibronectin, vWF, vitronectin and thrombospondin. It is involved in platelet aggregation.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD41
- Clone: P2
- Conjugate: ECD
- Isotype: IgG1
Handling
- Quantity: 100 tests
Applications
- Flow Cytometry (FC)