CD45RA (HI100) Antibody
Product Details
- Cat. No.
- 250970
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The CD45RA (HI100) antibody recognizes the 205/220-kDa isoform of leukocyte common antigen expressed on 40-50% peripheral CD4+ T cells, 50% peripheral CD8+ T cells and a portion of B cells and monocytes. Studies have shown that expression of different isoforms is characteristic of differentiated subset of hematopoietic cells (for instance CD45RA on naïve/ resting T cells and CD45RD on memory/ activated T cells; CD45RA on medullary thymocytes and CD45RD on cortical thymocytes). It is also reported that the pattern of 87% of B-ALL is CD45RA+/ CD45RO-, 70% of T-ALL is CD45RA-/ CD45RD+ and 78% of B-ALL is CD45RA+/ CD45RO+.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Clone: HI100
- Isotype: mouse IgG2a
- Gene: P08575, NP_002829
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Flow Cytometry (FC)
- Immunohistochemistry (IHC)