Product & ReviewsAntibodies

CD54-FITC, 84H10, 2 mL, ASR

Product Details

Cat. No.
IM0726U
Type
Flow Cytometry Reagents
Clonality
Monoclonal
Host
Mouse
Beckman Coulter Life Sciences

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Description

The CD54 antigen, previously known as ICAM-1 (InterCellular Adhesion Molecule-1), is a 90 kDa transmembrane glycoprotein. With seven potential N-linked glycosylation sites, its structure, as that of CD50 (ICAM-3) and CD102 (ICAM-2), is related to the Immunoglobulin family. The CD54 antigen mediates the adhesion of T lymphocytes with Antigen-Presenting Cells (APC) and is involved in T cell to T cell and T cell to B cell interactions. It is also involved in the adhesion of monocytes, lymphocytes and neutrophils to activated endothelium. It binds to the integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It is a receptor for the rhinovirus. It is expressed by endothelial cells and by many other cell types upon activation.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Dog (Canine), Human
  • Antigen: CD54
  • Clone: 84H10
  • Conjugate: FITC
  • Isotype: IgG1

Handling

  • Quantity: 2 mL

Applications

  • Flow Cytometry (FC)
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