CD54-FITC, 84H10, 2 mL, ASR
Product Details
- Cat. No.
- IM0726U
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The CD54 antigen, previously known as ICAM-1 (InterCellular Adhesion Molecule-1), is a 90 kDa transmembrane glycoprotein. With seven potential N-linked glycosylation sites, its structure, as that of CD50 (ICAM-3) and CD102 (ICAM-2), is related to the Immunoglobulin family. The CD54 antigen mediates the adhesion of T lymphocytes with Antigen-Presenting Cells (APC) and is involved in T cell to T cell and T cell to B cell interactions. It is also involved in the adhesion of monocytes, lymphocytes and neutrophils to activated endothelium. It binds to the integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It is a receptor for the rhinovirus. It is expressed by endothelial cells and by many other cell types upon activation.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Dog (Canine), Human
- Antigen: CD54
- Clone: 84H10
- Conjugate: FITC
- Isotype: IgG1
Handling
- Quantity: 2 mL
Applications
- Flow Cytometry (FC)