CD58 (HI58a) Antibody
Product Details
- Cat. No.
- 250975
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The CD58 (HI58a) antibody recognizes a 55-70 kDa membrane glycoprotein known as the lymphocyte function associated antigen-3 (LFA-3). CD58 antigen has wide distribution over many tissues, both hematopoietic and non-hematopoietic cells, including leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts. There are two isoforms of CD58 antigen: a glycosylphosphatidylinositol (GPI)- anchor form and a transmembrane form. Both forms are expressed on the same cell type, however erythrocytes only have the GPI- anchored isoform. CD58 is an adhesion molecule that binds to CD2 for cell signaling to T cells and NK cells.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Clone: HI58a
- Isotype: mouse IgG1
- Gene: P19256
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Flow Cytometry (FC)