CD6 (HI210) Antibody
Product Details
- Cat. No.
- 251051
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The CD6 (HI210) Antibody recognizes a 100-130 kDa type-I single-chain transmembrane glycoprotein, a receptor for CD166. CD6 is expressed at low levels on immature thymocytes and at high levels on mature thymocytes. CD6 is also expressed at high levels on peripheral blood T cells and at low levels on most peripheral blood B cells. High levels of CD6 are present in T-cell malignancies and certain B-cell malignancies including B-CLL. CD6 not only is expressed on all CD5+ B-CLL, but also on CD5- B-CLL, suggesting a broader distribution of CD6 than CD5 in B-cell malignancies. CD6 has also been found recently to be expressed in a minor subset of myeloid malignancies. CD6 functions as an adhesion molecule as well as a costimulatory molecule for T cell activation.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Clone: HI210
- Conjugate: PE-conjugated Antibody
- Isotype: mouse IgG1
- Gene: P30203
Handling
- Quantity: 2 ml
- Storage: Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Applications
- Flow Cytometry (FC)