The CD61 antigen (platelet glycoprotein GPIIIa) is the 110 kDa integrin β3 subunit, con-covalently associated with the integrin αIIb chain (CD41, platelet GPIIb) to form the GPIIb-IIIa complex (αIIb-β3 integrin). Independently of CD41, CD61 is also associated with the integrin αV (CD51) to form the vitronectin receptor. CD41/CD61 is expressed only by platelets and megakaryocytes, whereas CD51/CD61 is found on osteoclasts, endothelial cells, macrophages, fibroblasts, smooth muscle, synovial lining cells and renal glomeruli.
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD61
- Clone: SZ21
- Conjugate: PC5.5
- Isotype: IgG1