Product & ReviewsAntibodies
CD62P Antibody
Product Details
- Cat. No.
- 251211
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
CD62P (P-Selectin) is a Ca2+-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. CD62P mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand for CD62P is sialyl-Lewis X. Activation of CD62P mediates leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. Defects in CD62P have been linked to an increased susceptibility to ischemic stroke.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Chimpanzee, Dog (Canine), Guinea Pig, Human, Monkey, Mouse, Pig (Swine), Rabbit (Lapine), Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of mouse CD62P.
- Isotype: Rabbit Ig
- Gene: Q01102
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)