CD66b-APC-A750, 80H3, 0.5 mL, ASR
Product Details
- Cat. No.
- B08756
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The CD66 antigens were originally described as granulocyte-specific activation antigens, related to the carcino-embryonic antigen (CEA) previously described on colon cancer cells. The CEA/CD66 gene group belongs to the immunoglobulin (Ig) gene superfamily. Among the CD66 cluster, CD66b (also known as CGM6) is a glycosyl-phosphatidylinositol (GPI)-anchored glycoprotein of 95-100 kDa. CD66b is thought to play a role in the regulation of the adhesive activity of CD11/CD18 via signal transduction in neutrophils. It is strongly expressed by myelocytes, metamyelocytes, neutrophils and polymorphonuclear neutrophils. CD66b is weakly expressed by promyelocytes.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD66b
- Clone: 80H3
- Conjugate: APC-Alexa Fluor* 750
- Isotype: IgG1
Handling
- Quantity: 0.5 mL
Applications
- Flow Cytometry (FC)