Product & ReviewsAntibodies

CD7-APC-A750, 8H8.1, 0.5 mL, ASR

Product Details

Cat. No.
B16892
Type
Flow Cytometry Reagents
Clonality
Monoclonal
Host
Mouse
Beckman Coulter Life Sciences

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Description

The CD7 antigen is a membrane-embedded glycoprotein with a molecular weight of 40 kDa. It is expressed at an early stage of T lineage ontogeny, during the extrathymic prothymocytic formation. CD7 expression persists throughout T lymphocytes differentiation defining CD7 as a pan-T marker. It is also expressed on thymocytes, on the majority of resting T lymphocytes, and Natural Killer cells (NK), and on a subset of pre-B lymphocytes and B lymphocytes from foetal bone marrow. CD7 expression is also detected on pluripotent hematopoietic stem cells. Mature B-lymphocytes, cells from erythroid, myeloid and megacaryocytic lineage do not express the CD7 molecule. The CD7 molecule is involved in T lymphocytes activation. Its expression may be quantitatively up-regulated on stimulated T lymphocytes.*Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: CD7
  • Clone: 8H8.1
  • Conjugate: APC-Alexa Fluor* 750
  • Isotype: IgG2a

Handling

  • Quantity: 0.5 mL

Applications

  • Flow Cytometry (FC)
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