Product & ReviewsAntibodies

CD8 (HIT8a) Antibody

Product Details

Cat. No.
251053
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Abbiotec

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Description

The CD8 (HIT8a) antibody recognizes a 68-kDa type-I transmembrane glycoprotein that consists of two disulfide-linked chains that form alpha homodimers or alpha/beta heterodimers. The most frequent CD8 antigen is CD8 alpha/beta heterodimer, which is expressed on 13-48 % peripheral blood suppressor/cytotoxic T lymphocytes (Ts/Tc) and 70-80% thymocytes. In addition, a proportion of γδT cells and NK cells express CD8α homodimers. CD8β requires the presence of CD8a to be expressed on the cell surface. CD8 antigen is co-receptor for HLA class-I molecules.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Clone: HIT8a
  • Conjugate: PE-conjugated Antibody
  • Isotype: mouse IgG1
  • Gene: P01732, NP_001761

Handling

  • Quantity: 2 ml
  • Storage: Store at 4°C. Product is guaranteed 6 months from the date of shipment.

Applications

  • Flow Cytometry (FC)
Specificity rating
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