CD80-APC, MAB104, 0.5 mL, ASR
Product Details
- Cat. No.
- B30642
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The CD80 antigen (B7, BB1) is a highly glycosylated single-chain protein. Its extracellular domain consists of two Ig-like domains. This 60 kDa molecule shares with CD86 the capability to be the ligand for two structurally similar molecules expressed on T lymphocytes, CD28 and CD152 (CTLA-4). CD80 antigen is expressed on in vitro activated B lymphocytes after 24h stimulation and at maximal level 48-72h post activation. It is not expressed on the majority of resting B cells from peripheral blood but identifies a subpopulation of B cells that has been previously activated. The antigen is also expressed by HTLV-1 transformed T cells and activated monocytes. CD80 binding provides co-stimulatory signals for T cell activation.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD80
- Clone: MAB104
- Conjugate: APC
- Isotype: IgG1
Handling
- Quantity: 0.5 mL
Applications
- Flow Cytometry (FC)