Product & ReviewsAntibodies
CDH1 (7A2) Antibody
Product Details
- Cat. No.
- 253086
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CDH1 (Cadherin-1) is a cell adhesion protein, member of the cadherin family. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. E-cadherin (CDH1) is involved in mechanisms regulating cell-cell adhesion, mobility and proliferation of epithelial cells. CDH1 has a potent invasive suppressor role. CDH1 binds to integrin alpha-E/beta-7. Defects in CDH1 are the cause of gastric, endometrial, breast, ovary and thyroid cancers.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of human CDH1 expressed in E. coli.
- Clone: 7A2
- Isotype: Mouse IgG1
- Gene: P12830, NP_004351
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Western Blotting (WB)