Product & ReviewsAntibodies

CDH1 (7H12) Antibody

Product Details

Cat. No.
253080
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Abbiotec

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Description

CDH1 (Cadherin-1) is a cell adhesion protein, member of the cadherin family. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. E-cadherin (CDH1) is involved in mechanisms regulating cell-cell adhesion, mobility and proliferation of epithelial cells. CDH1 has a potent invasive suppressor role. CDH1 binds to integrin alpha-E/beta-7. Defects in CDH1 are the cause of gastric, endometrial, breast, ovary and thyroid cancers.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human, Monkey, Mouse
  • Antigen: Purified recombinant fragment of human CDH1 expressed in E. coli.
  • Clone: 7H12
  • Isotype: Mouse IgG1
  • Gene: P12830, NP_004351

Handling

  • Quantity: 0.1 ml
  • Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.

Applications

  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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