CDH5 Rabbit pAb
Product Details
- Cat. No.
- A12416
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human