Product & ReviewsAntibodies
CDKN1C/p57 Kip2 Rabbit mAb
Product Details
- Cat. No.
- A6843
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rabbit
Western blot - CDKN1C/p57 Kip2 Rabbit mAb (A6843)
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Description
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Biological Information
- Clonality: Monoclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
