Product & ReviewsAntibodies
CDKN2A Antibody
Product Details
- Cat. No.
- 200147
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
CDKN2A acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This interaction inhibits CDKs binding to cyclins D and phosphorylation of the retinoblastoma protein. Defects in CDKN2A are the cause of numerous cancers such as melanoma and astrocytoma.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CDKN2A.
- Isotype: Rabbit Ig
- Gene: P42771, NP_000068
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)