Product & ReviewsAntibodies

CDT1 hamster antibody (mAb)

Product Details

Cat. No.
61039
Type
Primary Antibody
Clonality
Monoclonal
Host
Hamster
Active Motif

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Description

CDT1 (chromatin licensing and DNA replication factor 1) is a key licensing factor which functions to allow DNA replication. It is recruited (along with CDC6) by the ORC (Origin Recognition Complex) to sites of DNA replication and helps form the pre-replicative complex (pre-RC). Its activity during the cell cycle is regulated by its association with the Geminin protein geminin, which both inhibits CDT1 activity during S phase in order to prevent unregulated DNA replication and also to inhibit CDT1 proteolysis.

Biological Information

  • Clonality: Monoclonal
  • Host: Hamster
  • Reactivity: Human
  • Isotype: IgG

Handling

  • Quantity: 100 ug
  • Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Applications

  • Western Blotting (WB)
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