CEP170 Rabbit pAb
Product Details
- Cat. No.
- A15370
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human