CFD Rabbit pAb
Product Details
- Cat. No.
- A8117
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - CFD antibody (A8117)
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Description
This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse
