Product & ReviewsAntibodies

CFTR Antibody

Product Details

Cat. No.
251639
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Abbiotec

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Description

Cystic fibrosis transmembrane conductance regulator (CFTR), a ABC transporter, is involved in the transport of chloride ions and regulates bicarbonate secretion in epithelial cells by regulating the SLC4A7 transporter. CFTR is localized in aggresome bodies when proteasome's degradative capacity is exceeded and lysosomal degradation is engaged via autophagy. Defects in CFTR are the cause of cystic fibrosis.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Bovine, Dog (Canine), Human, Mouse, Rat
  • Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CFTR.
  • Isotype: Rabbit Ig
  • Gene: P13569

Handling

  • Quantity: 0.1 mg
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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