CHD1 rat antibody (mAb) (Clone 2F11), sample
Product Details
- Cat. No.
- 39990
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our Antibody Directory.
Description
CHD1 (Chromo-ATPase/Helicase-DNA-binding protein 1 ) is a member of the CHD family of ATP-dependent chromatin remodeling factors implicated in RNA polymerase II transcriptional regulation. They are characterized by the presence of a double chromodomains (Chromatin Organization Modifier) and SNF2-related helicase/ATPase domains. The CHD1/CHD2 sub-family of CHD proteins also contain a C-terminal DNA binding domain that recognizes AT-rich sequences. CHD proteins alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. CHD1 has been shown to interact with histone H3 trimethylated at lysine 4 (H3K4Me3) and also is required for the maintenance of stem cell pluripotency.
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Human, Mouse
- Clone: 2F11
- Isotype: IgG2a
Handling
- Quantity: 10 ug
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Immunofluorescence (IF)
- Western Blotting (WB)