Product & ReviewsAntibodies
CHD3 (2G4) Antibody
Product Details
- Cat. No.
- 252948
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CHD3 (Chromodomain-helicase-DNA-binding protein 3) is a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse
- Antigen: Purified recombinant fragment of human CHD3 expressed in E. coli.
- Clone: 2G4
- Isotype: Mouse IgG1
- Gene: Q12873
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blotting (WB)