Product & ReviewsAntibodies
CHRNA4 Antibody
Product Details
- Cat. No.
- 251410
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
After binding acetylcholine, the neuronal acetylcholine receptor (CHRNA4) responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in CHRNA4 are the cause of nocturnal frontal lobe epilepsy type 1 (ENFL1), also symbolized ADNFLE. ENFL1 is an autosomal dominant epilepsy characterized by nocturnal seizures with hyperkinetic automatisms and poorly organized stereotyped movements.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CHRNA4.
- Isotype: Rabbit Ig
- Gene: P43681
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)