Product & ReviewsAntibodies
CK1 (3C10) Antibody
Product Details
- Cat. No.
- 252668
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CK1 (Cytokeratin-1) is an intermediate filament protein. CK1 regulates the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). Defects in CK1 are a cause of bullous congenital ichthyosiform erythroderma, also known as epidermolytic hyperkeratosis (EHK) or bullous erythroderma ichthyosiformis congenita of Brocq. BCIE is an autosomal dominant skin disorder characterized by widespread blistering and an ichthyotic erythroderma at birth that persists into adulthood.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of CK1 expressed in E. coli.
- Clone: 3C10F7, 3C10G5, PMC01, 4D12B3,3C10F7C11
- Isotype: Mouse IgG1
- Gene: P04264
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunohistochemistry (IHC)
- Western Blotting (WB)