Product & ReviewsAntibodies
CKIP-1 Antibody
Product Details
- Cat. No.
- 251643
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Casein kinase 2-interacting protein 1 (CKIP-1) plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). CKIP-1 targets CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). CKIP-1 inhibits tumor cell growth by inhibiting AKT-mediated cell-survival. CKIP-1 is involved in PI3K-regulated muscle differentiation, the regulation of AP-1 activity and the promotion of apoptosis induced by tumor necrosis factor TNF.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CKIP-1.
- Isotype: Rabbit Ig
- Gene: Q53GL0
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)