Product & ReviewsAntibodies
CLOCK Antibody
Product Details
- Cat. No.
- 252186
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
CLOCK (Circadian locomoter output cycles protein kaput) heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. CLOCK activates transcription of PER1 and PER2. This transcription is inhibited in a feedback loop by PER and CRY proteins. CLOCK has intrinsic histone acetyltransferase activity and this enzymatic function contributes to chromatin-remodeling events implicated in circadian control of gene expression. CLOCK acetylates primarily histones H3 and H4.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CLOCK.
- Isotype: Rabbit Ig
- Gene: O15516
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)