Product & ReviewsAntibodies
COBRA1 Antibody
Product Details
- Cat. No.
- 253121
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Cofactor of BRCA1 (negative elongation factor B, NELF-B, COBRA1) is an essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. COBRA1 can induce chromatin unfolding.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse, Rabbit (Lapine), Rat, Sheep (Ovine)
- Antigen: Recombinant full length human COBRA1 expressed in E. coli.
- Isotype: Mouse IgG1
- Gene: Q8WX92
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)