Collagen IV (Mouse) Antibody
Product Details
- Cat. No.
- 250485
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Type IV collagen is the major structural component of glomerular basement membranes forming a "chicken-wire" meshwork together with laminins, proteoglycans and entactin/nidogen. There are six type IV collagen isoforms, alpha 1(IV)-alpha 6(IV), each of which can form a triple helix structure with 2 other chains to generate type IV collagen network. Defects in type IV collagen are a cause of Alport syndrome autosomal recessive (APSAR), characterized by glomerulonephritis, renal failure, sensorineural deafness and eye abnormalities. Defects in type IV collagen are also a cause of benign familial hematuria (BFH). The antibody is directed against rodent alpha 1 isoform.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Mouse, Pig (Swine), Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of mouse type IV collagen (isoform alpha 1).
- Isotype: Rabbit Ig
- Gene: Q9QZR9
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)