Product & ReviewsAntibodies
Collagen type IV Antibody
Product Details
- Cat. No.
- 251737
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Type IV collagen (collagen type IV) is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Defects in collagen type IV are a cause of Alport syndrome autosomal recessive (APSAR). APSAR is characterized by progressive glomerulonephritis, glomerular basement membrane defects, renal failure, sensorineural deafness and specific eye abnormalities (lenticonous and macular flecks).
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Human collagen type IV.
- Clone: Col-30
- Isotype: Mouse IgG1
- Gene: P53420
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)