Product & ReviewsAntibodies
Connexin-43 Antibody
Product Details
- Cat. No.
- 251847
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Gap junction alpha-1 protein (connexin-43) is a transmembrane channel that, together with other connexins, forms a gap junction. Gap junctions allow low MW materials to flow from one cell to a neighboring cell. Defects in connexin-43 are the cause of autosomal dominant oculodentodigital dysplasia (ODDD), also known as oculodentoosseous dysplasia. ODDD is a highly penetrant syndrome presenting with craniofacial (ocular, nasal, dental) and limb dysmorphisms, spastic paraplegia, and neurodegeneration.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human connexin-43.
- Isotype: Rabbit Ig
- Gene: P17302
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Western Blotting (WB)