Product & ReviewsAntibodies
Connexin-45 Antibody
Product Details
- Cat. No.
- 250487
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Connexin-45 (Cx45) is a component of the gap junction, which consists of a cluster of closely packed pairs of transmembrane channels, the connexons ,through which materials of low molecular weight diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. Connexin-45 is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. Mutations in Cx45 are associated with oculodentodigital dysplasia and heart malformations.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Dog (Canine), Human, Mouse, Pig (Swine), Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence in the center region of human Connexin-45.
- Isotype: Rabbit Ig
- Gene: P36383
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)