Corynebacterium Diphtheriae Toxoid (11D9) Antibody
Product Details
- Cat. No.
- 250348
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Corynebacterium diphtheriae is a Gram-positive, non-motile bacterium that can cause serious illness in unvaccinated humans. C. diphtheriae infects the epithelial cells of the upper respiratory tract from where they secrete a potent toxin that is absorbed and disseminated through lymph channels and blood to the susceptible tissues of the body. The toxin is a single protein chain of 62 kDa which is "nicked" at proteolytic processing sites to produce an A chain of 21 kDa and a B chain of 40 kDa, held together by a disulfide bridge. The A-chain carries the ADP-ribosylation enzymatic activity responsible for the toxic action. This antibody reacts with diphtheria toxoid.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Bacteria, Corynebacterium diphtheriae
- Antigen: Diphtheria toxoid prepared from toxin purified from C. diphtheriae subsp. intermedius Park-Williams no. 8 by formaldehyde inactivation (2), and adsorbed to aluminum hydrtoxide gel
- Clone: 11D9
- Isotype: Mouse IgG1/k
- Gene: P00588
Handling
- Quantity: 0.2 mg
- Storage: Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)