Product & ReviewsAntibodies
CULLIN Antibody
Product Details
- Cat. No.
- 250489
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Cullin (Cullin-1, CUL1) is a core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, cullin serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cullin contributes to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Chicken, Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CULLIN.
- Isotype: Rabbit Ig
- Gene: Q86Y37
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)