Product & ReviewsAntibodies
CXCR4 Rabbit pAb
Product Details
- Cat. No.
- A12534
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - CXCR4 Antibody (A12534)
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Description
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
